Kieran Murphy
MB, BCH, BAO, BSC, LRCPI, LRCSI, FRCPC, FSIR
- Cost-effectiveness and willing-to-pay thresholds for vertebral augmentation of osteoporotic vertebral fractures, what are they based on: a systematic review
CONCLUSIONS: Both VP and BK were judged cost-effective alternatives to CM for OVFs in economic studies and were within WTP thresholds in multiple […]
- Chromatin regulators in the TBX1 network confer risk for conotruncal heart defects in 22q11.2DS
Congenital heart disease (CHD) affecting the conotruncal region of the heart, occurs in 40-50% of patients with 22q11.2 deletion syndrome […]
- A Novel Tissue Preservation and Transport Solution as a Substitute for Formalin
Formalin, a common laboratory fixative, is a type 1 carcinogen; a biohazard with risks, environmental, disposal, and legal costs; and a chemical […]
- Role of Antioxidant Vitamins and Other Micronutrients on Regulations of Specific Genes and Signaling Pathways in the Prevention and Treatment of Cancer
Cancer is an escalating global issue, with 19.3 million new cases and 9.9 million deaths in 2020. Therefore, effective approaches to prevent cancer […]
- The Acute Effect of Multi-Ingredient Antioxidant Supplementation following Ionizing Radiation
Radiation exposure is an undeniable health threat encountered in various occupations and procedures. High energy waves in ionizing radiation cause […]
- Lead-Dust Contamination on Radiation Protection Apparel
CONCLUSIONS: A high prevalence of surface lead-dust contamination was detected on RPAs using a rapid qualitative test. There is currently no […]
- (Epi)genomic adaptation driven by fine geographical scale environmental heterogeneity after recent biological invasions
Elucidating processes and mechanisms involved in rapid local adaptation to varied environments is a poorly understood but crucial component in […]
- A Dietary Antioxidant Formulation Ameliorates DNA Damage Caused by γ-Irradiation in Normal Human Bronchial Epithelial Cells In Vitro
Antioxidants can be used as radioprotectants to reduce DNA damage due to exposure to radiation that could result in malignancies, including lung […]
- Ecological Review of the Ciona Species Complex
AbstractThe set of four closely related solitary ascidians Ciona spp. were once considered a single cosmopolitan species, Ciona intestinalis, but are […]
- Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Schizophrenia has a heritability of 60-80%¹, much of which is attributable to common risk alleles. Here, in a two-stage genome-wide association […]
- One year of psychiatric presentations to a hospital emergency department during COVID-19
CONCLUSIONS: Psychiatric presentations to the ED have increased during the first year of the COVID-19 pandemic in contrast to a decrease in […]
- Cost-effectiveness studies of vertebral augmentation for osteoporotic vertebral fractures: a systematic review
CONCLUSIONS: Both VP and BK, have been shown to be cost-effective alternatives to CM for osteoporotic vertebral fractures in diverse […]
- Tuning the mechanical impedance of disordered networks for impact mitigation
Disordered-Network Mechanical Materials (DNMM), comprised of random arrangements of bonds and nodes, have emerged as mechanical metamaterials with […]
- Intradiscal oxygen-ozone chemonucleolysis versus microdiscectomy for lumbar disc herniation radiculopathy: a non-inferiority randomized control trial
CONCLUSIONS: Intradiscal oxygen-ozone chemonucleolysis for single-level lumbar disc herniations unresponsive to medical management, met the […]
- Vitamin-Containing Antioxidant Formulation Reduces Carcinogen-Induced DNA Damage through ATR/Chk1 Signaling in Bronchial Epithelial Cells In Vitro
Lung cancer has the highest mortality rate worldwide and is often diagnosed at late stages, requiring genotoxic chemotherapy with significant side […]